VIP
5mg
❄️Lyophilized powder (not reconstituted)
Discount per Quantity
| Quantity | Discount | Price per Unit |
|---|---|---|
| 5 - 10 | 10% | €37.79 |
| 11 - 20 | 15% | €35.69 |
| 21+ | 20% | €33.59 |
Rigorous third-party testing
Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.
Total: €41.99
VIP is supplied as a catalogued research material in 5 mg.
“VIP” alone does not establish the terminal form. Aviptadil is the mature 28-residue C-terminally amidated peptide, while a separate free-acid record differs by elemental composition, mass, CAS and database identity. The batch sequence and terminal group must be confirmed before registry fields are selected [1–3].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Vasoactive Intestinal Peptide |
| Material category | Neuropeptide |
| Sequence | H-HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 |
| Molecular formula | C147H238N44O42S |
| Average molecular mass | 3325.9 g/mol |
| CAS Registry Number | 40077-57-4 |
| PubChem CID | CID 16132307 |
| Structural features | A 28-amino acid linear peptide with a C-terminal amide. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in water or aqueous buffers. Reconstitute with sterile water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Vasoactive Intestinal Peptide is a 28-amino acid neuropeptide that belongs to the glucagon/secretin superfamily. It is widely distributed in the central and peripheral nervous systems.
Research background and published evidence
Published research
Appropriate contexts include VPAC1 and VPAC2 receptor binding, cAMP signalling, peptide-fragment structure–activity work and analytical discrimination of amidated versus free-acid material. PACAP-family comparisons require their own exact standards [1–3].
Current scientific understanding
Results for aviptadil, free-acid VIP, PACAP or a separately manufactured medicinal formulation are not automatically interchangeable. Receptor-assay observations do not establish human-use safety, efficacy or suitability for this batch.
Aviptadil/VIP has medicinal and investigational regulatory history.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | VIP/aviptadil, conditional on C-terminal amidation confirmation | PACAP-27, a distinct secretin-family peptide |
| Structural distinction | VIP-specific 28-residue sequence with VPAC receptor profile | Different sequence and PAC1/VPAC pharmacological reference profile |
| Analytical implication | Confirm C-terminal amide versus free acid, intact mass and counter-ion | Requires a distinct sequence-specific reference standard |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution's approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] FDA GSRS. Aviptadil substance record.
- [2] KEGG Drug. Aviptadil record.
- [3] Review of VIP biosynthesis and amidation.
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution's risk assessment. Use only storage and stability information linked to the exact material form and batch.