Thymosin Alpha-1
5mg
❄️Lyophilized powder (not reconstituted)
Discount per Quantity
| Quantity | Discount | Price per Unit |
|---|---|---|
| 5 - 10 | 10% | €39.59 |
| 11 - 20 | 15% | €37.39 |
| 21+ | 20% | €35.19 |
Rigorous third-party testing
Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.
Total: €43.99
Thymosin Alpha-1 is supplied as a catalogued research material in 5 mg.
Thymosin alpha-1 (thymalfasin) is a discrete N-acetylated 28-residue peptide. Exact identity requires confirmation of N-acetylation, the free C-terminal acid and the supplied counter-ion; it must not be confused with heterogeneous Thymalin or other thymosins [1,2].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Thymalfasin, Tα1 |
| Material category | Immunomodulator |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH |
| Molecular formula | C129H215N33O55 |
| Average molecular mass | 3109.32 g/mol |
| CAS Registry Number | 62304-98-7 |
| PubChem CID | CID 16132132 |
| Structural features | A 28-amino acid linear peptide, N-terminally acetylated. It is the active fragment of prothymosin alpha. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in sterile or bacteriostatic water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Thymosin Alpha-1 is a synthetic peptide corresponding to the N-terminal 28 amino acids of prothymosin alpha. It is a potent immunomodulator used in the treatment of viral infections and as an immune adjuvant.
Research background and published evidence
Published research
Appropriate contexts include peptide identity and degradation, sequence-specific analytical method development, and model-specific in-vitro dendritic-cell or innate-signalling experiments. Findings remain dependent on the exact experimental model and material [1–3].
Current scientific understanding
Model-specific immune-signalling observations and information for separately manufactured medicinal products do not establish performance, safety or suitability of this catalogue batch. Thymalin-mixture evidence is not transferable.
Thymalfasin is used as a medicinal active substance in some jurisdictions.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Thymosin alpha-1: one N-acetylated 28-residue peptide | Thymalin: compositionally heterogeneous thymic peptide material |
| Structural distinction | One defined sequence with N-acetylation | Multiple peptide fractions dependent on source and process |
| Analytical implication | Sequence-specific intact mass, acetylation and purity methods apply | Requires mixture fingerprint and component-distribution controls |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution's approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Thymalfasin compound record.
- [2] Primary isolation and sequence report for thymosin alpha-1.
- [3] In-vitro dendritic-cell study of thymosin alpha-1.
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution's risk assessment. Use only storage and stability information linked to the exact material form and batch.