Melanotan 1
10mg
❄️Lyophilized powder (not reconstituted)
Discount per Quantity
| Quantity | Discount | Price per Unit |
|---|---|---|
| 5 - 10 | 10% | €35.99 |
| 11 - 20 | 15% | €33.99 |
| 21+ | 20% | €31.99 |
Rigorous third-party testing
Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.
Total: €39.99
Melanotan 1 is supplied as a catalogued research material in 10 mg.
The page may equate Melanotan 1 with NDP-alpha-MSH or afamelanotide only if the supplier specification and batch CoA confirm the full 13-residue sequence, stereochemistry, terminal modifications and salt. A market name alone does not establish identity with the authorized active substance.
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Afamelanotide, [Nle4, D-Phe7]-alpha-MSH, Scenesse |
| Material category | Melanocortin receptor agonist |
| Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Molecular formula | C78H111N21O19 |
| Average molecular mass | 1646.88 g/mol |
| CAS Registry Number | 75921-69-6 |
| PubChem CID | CID 9831662 |
| Structural features | Synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) with two substitutions (Met4→Nle, L-Phe7→D-Phe). N-terminally acetylated and C-terminally amidated. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in bacteriostatic water or sterile water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
A potent agonist of the melanocortin 1 receptor (MC1R) which stimulates melanogenesis (skin pigmentation). The INN is Afamelanotide.
Research background and published evidence
Published research
NDP-alpha-MSH/afamelanotide has been investigated as a stabilized linear melanocortin analogue in receptor and biochemical research. Structural interpretation depends on the D-Phe substitution, terminal modifications and exact salt form.
Current scientific understanding
Literature or regulatory data for a characterized afamelanotide medicinal product do not authenticate this catalogue powder, its salt stoichiometry, purity, formulation or comparability. Data for cyclic Melanotan II are not transferable.
Afamelanotide is the active substance in an EU-authorized prescription medicinal product; a Melanotan 1 research powder is not that authorized product.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Conditional linear NDP-alpha-MSH/afamelanotide sequence assignment | Melanotan II: shorter cyclic lactam melanocortin analogue |
| Structural distinction | Linear 13-residue peptide with N-acetylation, Nle4, D-Phe7 and C-terminal amide | Melanotan II has a different sequence and an Asp-Lys side-chain lactam ring |
| Analytical implication | Confirm full sequence, D-Phe stereochemistry, terminal groups, intact mass, purity and acetate stoichiometry | Melanocortin-receptor activity or market naming cannot distinguish this linear material from MT-II |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution's approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem CID 16197727 — Afamelanotide free moiety
- [2] FDA chemistry review — afamelanotide structure and acetate characterization
- [3] EMA EPAR — SCENESSE (afamelanotide)
- [4] Peptides — primary structural report on the stabilized alpha-MSH analogue
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution's risk assessment. Use only storage and stability information linked to the exact material form and batch.