Kisspeptin
10mg
❄️Lyophilized powder (not reconstituted)
Discount per Quantity
| Quantity | Discount | Price per Unit |
|---|---|---|
| 5 - 10 | 10% | €31.49 |
| 11 - 20 | 15% | €29.74 |
| 21+ | 20% | €27.99 |
Rigorous third-party testing
Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.
Total: €34.99
Kisspeptin is supplied as a 10 mg catalogue research material. The catalogue product corresponds to human Kisspeptin-10 (KP-10), the C-terminal decapeptide of the KISS1 precursor. Exact material form (salt, counter-ion, hydration) should be confirmed from the batch CoA and SDS.
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | Kisspeptin-10; KP-10; Metastin (45-54); KISS1 (112-121) |
| Material category | Synthetic amidated decapeptide; C-terminal fragment of the human KISS1 precursor |
| Sequence | H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2) |
| Molecular formula | C63H83N17O14 for the free amidated decapeptide; salts and solvates differ. |
| Average molecular mass | 1302.44 g/mol for the free amidated decapeptide. |
| CAS Registry Number | 374675-21-5 for human Kisspeptin-10, conditional on exact-form confirmation. |
| PubChem CID | CID 25240297 for human Kisspeptin-10, conditional on exact-form confirmation. |
| Structural features | 10 residues with C-terminal amidation; corresponds to the last 10 residues of the KISS1 precursor and shares the conserved C-terminal Arg-Phe-NH2 motif of the RFamide family. |
| Appearance | White to off-white lyophilised powder. |
| Solubility | Highly hydrophobic. Reconstitute with 0.6% acetic acid water; not readily soluble in plain bacteriostatic or sterile water. |
| Physical form | Catalogue vial; the exact physical state, salt or counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
| Catalogue presentation | 10 mg |
| Batch identity and quality documentation | Lot-specific identity and available analytical reports must be verified against the CoA entry associated with the exact product size and batch. |
Registry values apply only to the matching KISS1 fragment, species sequence, termini and exact material form. Batch records take precedence over family-level literature identifiers.
Research background and published evidence
Published research
KISS1-derived peptides — including the decapeptide Kisspeptin-10 — have been studied as ligands of the KISS1R/GPR54 receptor in receptor, cellular and physiological research [1,3,4]. Their shared C-terminal RFamide motif does not make Kisspeptin-54, -14, -13 and -10 analytically interchangeable.
Current scientific understanding
Findings are isoform-, species-, matrix- and assay-specific. Results obtained with human Kisspeptin-10, for example, should not be assigned to Kisspeptin-54, a non-human sequence or an unspecified terminal form without direct comparability.
Technical comparison
| Aspect | Kisspeptin-10 (this catalogue material) | Longer KISS1 isoforms |
|---|---|---|
| Identity | Defined amidated decapeptide when sequence and terminal form match the CoA [2] | Kisspeptin-54, -14 or -13 — distinct N-terminal extensions of the same C-terminal decapeptide core |
| Structural distinction | Ten-residue human sequence with a defined C-terminal amide | Additional N-terminal residues; different molecular mass, formula and registry identifiers |
| Analytical implication | KP-10 intact-mass, sequence and terminal-form evidence authenticate this material only | KP-10 identifiers do not authenticate longer isoforms or species variants |
Quality and testing
Quality information is batch- and presentation-specific. Use only a report linked to the exact size and lot.
Chromatographic purity, molecular identity, net peptide content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, matching CoA and SDS. Because Kisspeptin-10 is highly hydrophobic, plain bacteriostatic water is not a suitable reconstitution solvent — use 0.6% acetic acid water for laboratory reconstitution.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution's approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] UniProt Q15726 — KiSS-1 receptor ligand precursor, human.
- [2] PubChem CID 25240297 — human Kisspeptin-10 exact-form record.
- [3] Journal of Biological Chemistry — KISS1-derived peptides as GPR54 ligands.
- [4] Nature — identification of GPR54 ligands derived from KISS1.
Frequently Asked Questions
Does one CAS number apply to every kisspeptin?
No. Registry identifiers are isoform- and material-form-specific. The CAS number and PubChem CID listed above apply to human Kisspeptin-10 only.
What does an analytical purity result mean?
It is method- and report-specific. An HPLC area percentage does not by itself establish molecular identity, net content or the other quality attributes listed above.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution's risk assessment. For reconstitution use 0.6% acetic acid water rather than plain bacteriostatic water.