Sermorelin
10mg
❄️Lyophilized powder (not reconstituted)
Discount per Quantity
| Quantity | Discount | Price per Unit |
|---|---|---|
| 5 - 10 | 10% | €53.99 |
| 11 - 20 | 15% | €50.99 |
| 21+ | 20% | €47.99 |
Rigorous third-party testing
Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.
Total: €59.99
Sermorelin is supplied as a catalogued research material in 10 mg.
Sermorelin is the C-terminally amidated 1–29 fragment of human growth-hormone-releasing hormone. The free peptide and acetate or hydrated materials have different formula treatment; C-terminal amidation and exact counter-ion must be confirmed from the batch identity record [1,2].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | GRF (1-29), GHRH (1-29), Geref, Somatocrinin (1-29)-amide |
| Material category | Growth Hormone Secretagogue |
| Sequence | H-YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2 |
| Molecular formula | C149H246N44O42S |
| Average molecular mass | 3357.9 g/mol |
| CAS Registry Number | 86168-78-7 |
| PubChem CID | CID 16129624 |
| Structural features | A 29-amino acid peptide corresponding to the N-terminal segment of human growth hormone-releasing hormone (GHRH) with C-terminal amidation. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in bacteriostatic water or sterile water for injection. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Sermorelin is a synthetic peptide analogue of GHRH used as a diagnostic agent to assess pituitary function and for off-label anti-aging purposes.
Research background and published evidence
Published research
Appropriate research contexts include GHRH-receptor binding and signalling, primary pituitary-cell assays, peptide-fragment structure–activity studies and analytical separation from modified GHRH analogues [1–3].
Current scientific understanding
Historical medicinal-product or human-study information does not authenticate this catalogue material and must not be converted into efficacy, dosing or suitability claims. GHRH analogues with substitutions or acylation are not interchangeable with sermorelin.
Sermorelin has a history as a medicinal active substance.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Sermorelin: unmodified human GRF(1–29)-NH₂ sequence | Tesamorelin or CJC no-DAC, which contain acylation, length or residue substitutions |
| Structural distinction | 29 native GRF residues and a C-terminal amide | Different exact primary structure and/or N-terminal modification |
| Analytical implication | Confirm C-terminal amide, sulfur-containing sequence and counter-ion | Requires a separate exact-form reference standard |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution's approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Sermorelin compound record.
- [2] FDA GSRS. Sermorelin acetate substance record.
- [3] Primary pituitary-cell study of GRF fragments. Biochemical and Biophysical Research Communications (1984).
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution's risk assessment. Use only storage and stability information linked to the exact material form and batch.